This week the pharmaceutical company Moderna will start its human trials for this HIV vaccine. Its HIV vaccine will be the first of its kind to use Messenger RNA (MRNA) an approach Moderna used in its effective COVID-19 vaccination. The clinical trials will start Aug 19, 2021, and end sometime around Spring 2023 according to the National Institute of Health Trial Registry. It will involve 56 HIV-negative participants age 18-56. Participants will be given one of two forms of MRNA to cause the body to form defenses against HIV infection. In the past HIV vaccines used inactivated forms of the virus. Previous trials have shown that those forms of vaccines didn’t produce any immune responses. In fact on trial in Thailand canceled one trial during the 2000s after the inactive forms of the virus actually increased people’s chances of catching HIV rather than prevent HIV infection.
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